Endometriosis linked to increased cardiovascular risk for women in Sweden and Denmark

Approximately 250,000 women in Sweden suffer from endometriosis, a condition where cells from the uterine lining grow outside the uterus, often on the ovaries and abdominal wall. This can lead to severe pain and significant suffering for patients.

Recent research from Denmark has found that endometriosis may also increase the risk of cardiovascular diseases. The study followed over 300,000 women for up to 45 years and revealed that those with endometriosis had about a 20% higher risk of stroke and a 35% increased risk of heart attack. Experts stress the importance of considering female-specific risk factors in cardiovascular disease prevention.

Karin Schenk-Gustafson, a cardiologist and professor at Karolinska Institute, criticized the healthcare system for not adequately addressing these risks in women compared to men, who are routinely questioned about potential heart disease indicators like erectile dysfunction. She emphasized the need for doctors to also consider factors like preeclampsia, early menopause, and endometriosis.

The precise reasons why endometriosis raises the risk for heart disease remain unclear. One theory suggests that chronic pain and inflammation could lead to stress and high blood pressure. Additionally, lower estrogen levels—essential for heart protection—are thought to play a role, especially as treatments for endometriosis often involve reducing estrogen levels.

Experts recommend that gynecologists inform their patients with endometriosis about this increased risk, although they note that while there is a heightened risk, it is not necessarily alarming. Focusing on overall health and addressing risk factors like hypertension, obesity, and stress is advised. The findings will be presented at the upcoming European Society of Cardiology congress.